Review: dopamine agonists are not effective for cocaine dependence
نویسندگان
چکیده
منابع مشابه
Review: antidepressants are not effective for cocaine dependence.
Data sources Studies were identified by searching the Cochrane Controlled Trials Register, Medline (1966–2000), EMBASE/ Excerpta Medica (1980–2000), LILACS (1982–2000), PsycLIT (1974–2000), Biological Abstracts (1982– 2000), and the trials’ registers of 3 Cochrane review groups; by reviewing book chapters on the treatment of cocaine dependence; and by contacting pharmaceutical companies and exp...
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Dopamine-deficient (DA-/-) mice were created by targeted inactivation of the tyrosine hydroxylase gene in dopaminergic neurons. The locomotor activity response of these mutants to dopamine D1 or D2 receptor agonists and l-3,4-dihydroxyphenylalanine (l-DOPA) was 3- to 13-fold greater than the response elicited from wild-type mice. The enhanced sensitivity of DA-/- mice to agonists was independen...
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ژورنال
عنوان ژورنال: Evidence-Based Mental Health
سال: 2002
ISSN: 1362-0347
DOI: 10.1136/ebmh.5.3.83